In the replace of this review undertaken in November 2008, five randomised managed trials involving a complete of 374 contributors met the inclusion criteria for this review and in contrast tramadol to placebo. Proof from these trials showed that 100 to four hundred mg of tramadol is an effective symptomatic remedy for peripheral neuropathic pain. One trial involving lower than 40 members compared tramadol to morphine, and one involving 21 individuals in contrast tramadol to clomipramine. It was not attainable to attract conclusions from these two trials as to which of these medication is more effective.
Treatment with tramadol could trigger negative effects, together with constipation, nausea, sedation and a dry mouth, all of which resolve after stopping treatment. Within the trials reviewed here, one person out of eight handled with tramadol left the trial due to aspect effects. Tramadol can also be related to a small risk of seizures (suits) and its use is contraindicated in individuals with a history of epilepsy.
Posted in: Tramadol
