BRAND NAME: Ultram, Ultram ER
DRUG CLASS AND MECHANISM: Tramadol is a person-made (artificial) analgesic (pain reliever). Its actual mechanism of action is unknown but comparable morphine. Like morphine, tramadol binds to receptors in the brain (opioid receptors) which are necessary for transmitting the sensation of ache from all through the body to. Tramadol, like other narcotics used for the therapy of pain, may be abused. Tramadol will not be a nonsteroidal antiinflammatory drug (NSAID) and does not have the elevated threat of stomach ulceration and internal bleeding that may happen with NSAIDs.
PRESCRIPTION: Sure
GENERIC AVAILABLE: Yes
PREPARATIONS: Tablets (instant launch): 50 mg. Tablets (prolonged launch): a hundred, 200, and 300 mg.
STORAGE: Store at room temperature, 15-30 C (fifty nine-86 F). Retailer in a sealed container.
PRESCRIBED FOR: Tramadol is used within the administration of moderate to reasonably severe pain. Prolonged release tablets are used for moderate to reasonably extreme power ache in adults who require steady treatment for an prolonged period.
DOSING: The beneficial dose of tramadol is 50-a hundred mg (quick release tablets) each 4-6 hours as needed for pain. The utmost dose is 400 mg/day. To enhance tolerance sufferers needs to be started at 25 mg/day, and doses could also be elevated by 25 mg every three days to achieve one hundred mg/day (25 mg 4 times each day). Thereafter, doses will be elevated by 50 mg every 3 days to achieve 200 mg day (50 mg four times daily). Tramadol could also be taken with or without food.
Recommended dose for extended release tablets is a hundred mg day by day which may be elevated by a hundred mg each 5 days but to not exceed 300 mg /day. Extended release tablets must be swallowed whole and not crushed or chewed.
DRUG INTERACTIONS: Carbamazepine (Tegretol, Tegretol XR , Equetro, Carbatrol) reduces the impact of tramadol by growing its inactivation in the body. Quinidine (Quinaglute, Quinidex) reduces the inactivation of tramadol, thereby increasing the concentration of tramadol by 50%-60%. Combining tramadol with monoamine oxidase inhibitors (for example, Parnate) or selective serotonin inhibitors ((SSRIs, for example, fluoxetine Prozac]) may lead to severe unintended effects corresponding to seizures or a condition known as serotonin syndrome.
Tramadol could increase central nervous system and respiratory melancholy when combined with alcohol, anesthetics, narcotics, tranquilizers or sedative hypnotics.
PREGNANCY: The protection of tramadol during pregnancy has not been established.
NURSING MOTHERS: The protection of tramadol in nursing mothers has not been established.
SIDE EFFECTS: Tramadol is usually effectively tolerated, and uncomfortable side effects are often transient. Commonly reported side effects embrace nausea, constipation, dizziness, headache, drowsiness, and vomiting. Much less commonly reported unwanted side effects embrace itching, sweating, dry mouth, diarrhea, rash, visible disturbances, and vertigo. Some patients who received tramadol have reported seizures. Abrupt withdrawal of tramadol could result in anxiousness, sweating, insomnia, rigors, ache, nausea, diarrhea, tremors, and hallucinations.
Posted in: 
