You shouldn't take this medication if you're allergic to it, in case you are intoxicated (drunk), or if you have lately used any of the next drugs:
- alcohol;
- tramadol (Ultram) or narcotic ache medication;
- sedatives or tranquilizers (reminiscent of Valium);
- medication for despair or anxiousness;
- medication for psychological sickness (comparable to bipolar disorder, schizophrenia); or
- avenue drugs.
Seizures have occurred in some individuals taking acetaminophen and tramadol. Your risk of a seizure may be larger if you have any of those circumstances:
- a historical past of drug or alcohol addiction;
- a history of epilepsy or different seizure dysfunction;
- a history of head damage;
- a metabolic disorder;
- an an infection of your brain or spinal wire, corresponding to meningitis or encephalitis;
- if you're additionally taking an antidepressant, temper stabilizer, or another narcotic ache medication; or
- if in case you have taken an MAO inhibitor akin to isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the previous 14 days.
When you've got any of those other situations, it's possible you'll need a dose adjustment or particular assessments:
- kidney disease;
- liver disease;
- asthma or other respiratory dysfunction;
- a abdomen dysfunction; or
- a historical past of melancholy, psychological sickness, or suicide attempt.